A Southwark branch of Pret A Manger is among the thirty shops the chain will close, which could cost more than 1,000 jobs nationwide.
The outlet of the coffee shop on The Cut, between Southwark and Waterloo stations, is among the eleven branches in London set to close.
It comes as the pandemic has sharply hit sales, with the chain saying it needed to reduce staff as footfall is less and more office staff are working from home.
The group’s chief executive, Pano Christou, said: “It’s a sad day for the whole Pret family, and I’m devastated that we will be losing so many employees.
“But we must make these changes to adapt to the new retail environment.”
The chain had closed all shops in March as lockdown was announced. Since then, it had reopened around 300 of its stores for takeaway.