Fifteen fire engines and around 100 firefighters are dealing with a fire on the roof of a block of flats on Creek Road in Deptford.
Some thirteen people left the building before the fire brigade arrived. There have been no reports of any injuries.
The fire brigade was called just after 1pm. The cause of the fire is unknown. Fire crews from Deptford and surrounding fire stations are at the scene.
Bermondsey murder: four victims of Bonamy Estate stabbing named
Traffic is backed up around the street and people are being told to avoid the area.