Road works this weekend include Thames Water work in Deptford Bridge and utility works in Upper Thames Street.
The A2 has temporary traffic lights in place at the junction of Deptford bridge with Greenwich High Road.
Traffic is slow on approaches, with eastbound delays from New Cross Station, and westbound through Blackheath, according to TfL.
The A3211 also has temporary traffic lights in place, between Blackfriars Bridge and Southwark Bridge until midnight on Sunday.
Meanwhile, A300 Southwark Brdge is closed until 10pm on Sunday.
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